Chunk #51 — ONLINE METHODS — Classification of tissues/cell types for system-level validation of the results of the multiple-tissue analysis of gene expression
We used the classification for visualization used in Figure 2, classifying the top tissue or cell type for each trait with a significant enrichment into one of the eight systems (excluding “Other”) in the Figure 2 legend. There were three phenotypes whose top tissue fell in the “Other” category; two of these we classified into a new “Reproductive” category. The last one, serous membrane, did not have any comparable tissues in our chromatin data and so we instead attempted to replicate the second most significant result for that phenotype.
