Our analyses focused on a subset of 759 participants (426 women, mean age 19.65±1.24) with BOLD fMRI data surviving a stringent multi-level quality control procedure (Supplementary Table 1). Of these 759 participants, 127 (55 women; mean age 19.79±1.21) met criteria for at least one current Axis I or select Axis II (borderline or antisocial personality disorder) diagnosis according to DSM-IV. The majority of these individuals (n=86; 35 women, mean age 19.94±1.15) were diagnosed with AUD (Supplementary Table 2). Since our study focuses on inter-individual variability in problem drinking, we did not exclude individuals with categorical disorders from analyses. Furthermore, we used presence of a current alcohol-related disorder (alcohol abuse or dependence) as a dependent variable in a subset of analyses. Notably, participants were required to pass a breathalyzer test before scanning to ensure they were not acutely intoxicated at the time of data collection. In addition, participants were asked to refrain from using any psychoactive substances while participating in the study and notified that they would be subject to a random drug screen on the day of their scan. Immediately
