Similar compensatory mechanisms are suggested in previous studies (Tapert et al., 2007), where adolescents with histories of chronic marijuana use show increased BOLD response compared to controls in areas connected to the occipital-cuneus (i.e., occipital gyri). Likewise, findings of greater brain activation in adult MJ+ALC users is thought to be associated with regional brain compensation (Chang & Chronicle, 2007; Pfefferbaum et al., 2001).
