events, namely those associated with financial difficulties, and less robustly illness/injury, in interaction with the 5-HTTLPR genotype to influence the emergence of depressive symptomatology. The findings corroborate earlier findings concerning the role of the 5-HTTLPR genotype in depression in modulating the effects of negative life events,1, 12 and have also potentially thrown light on the contradictory findings of several studies and meta-analyses,16 by showing that different types of recent life events and stresses may have a differential role in the emergence of depression, with only the effect of certain types of life events being modulated by 5-HTTLPR.