Chunk #61 — Conclusions

Source

Characterizing and measuring bias in sequence data.

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yes

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Bias in read accuracy (and not just coverage) is also important. It is well known that some loci on the genome sequence badly. Often this behavior is associated with polymerase slippage. In this work we defined assays, like those for coverage bias, which can be used to track error bias, and evaluated these assays on the same data sets used for coverage bias.