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Chunk #34 — Materials and Methods — Subjects

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A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.
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few had developed COPD yet. All LHS and WI participants were smoking at the time they participated in the study, but 43% of the UT cohort had been tobacco abstinent for the previous two years. The LHS subjects were restricted to European Americans for whom DNA was available. De-identified demographic and phenotypic data was provided from the LHS limited access dataset by the NIH/NHLBI.