The interactive GWAS diagram uses the Web Ontology Language/Resource Description Framework (OWL/RDF, https://www.w3.org/OWL/) for representation of the Catalog data and was previously hosted separately from the main GWAS Catalog. The new diagram portal (www.ebi.ac.uk/gwas/diagram) is now integrated with the new public Catalog infrastructure providing a uniform look and feel and improving transition for users between search and visualization. It is now possible to search the Catalog for a trait or SNP of interest directly from the pop-up information window for each trait. The redevelopment of the diagram generation software using a Virtuoso triplestore to represent the underlying data, has led to more than 1000-fold improvement in diagram generation time, and diagram and data releases are now synchronized weekly. Current and older versions of the GWAS diagram are downloadable providing users with high quality diagram images for publications and presentations and enabling the construction of a diagram time series. The full GWAS Catalog is also available in OWL/RDF format, allowing users to install their own triple store and run their own version of the diagram generation software as well as query the GWAS Catalog in SPARQL or another graph querying language.
