receptor carriers will be manifested with either three or four glycosylation sites. The loss of the glycosylation site may be significant in decreasing the opioid receptor’s ability to dimerize with other opioid receptors35. For example, the loss of the glycosylation site in β1-adrenergic receptors has been reported to markedly decrease both the ability of the receptor to dimerize and reach the cell surface36.
