Results of logistic regression analyses predicting 1990–2004 suicide rates from MLDA exposure, adjusting for birth state and birth year fixed effects are shown in Table 2. There was no significant main effect for MLDA on suicide (OR=1.02, p=0.35). Little change in the point estimate was observed when adjusting for race or sex. However, inclusion of a sex-by-MLDA interaction suggested that women who were exposed to lower MLDA had a statistically significant 12% elevated risk for suicide during this period (OR=1.12, 95% CI: 1.05, 1.18, p=0.0003). The odds ratio associating more permissive MLDA and suicide risk for men was slightly below one (0.97, 95% CI: 0.95, 1.00, p=0.048), and nominally statistically significant. The interaction between MLDA and sex was highly significant (p=<0.0001). Limiting the analysis to likely non-movers, i.e., individuals who died in their state of birth, or who lived in their state of birth for the 1990 census, had essentially no effect on parameter estimates (See Supplemental Table 1). Likewise, using state-of-residence, rather than state-of-birth, to estimate MLDA exposure had little impact (See Supplemental Table 2). Inclusion of educational attainment
