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Chunk #22 — 2 Materials and Methods — 2.8 fMRI Analysis for Localizing the DMN

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Simultaneous EEG-fMRI reveals a temporal cascade of task-related and default-mode activations during a simple target detection task.
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Because our single-trial findings included correlates consistent with DMN, we performed ICA on the functional image data to locate the DMN, which is an established method used to study resting-state functional networks not associated with any task (De Luca et al., 2006; Fox et al., 2007). To prevent investigator bias, we used a template-matching algorithm to automatically determine the DMN component for each subject (template obtained from the Neurosynth database of Yarkoni et al., 2011), and we found the group mean DMN component in MNI space. Manual DMN component selection was consistent with our algorithm output.