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Chunk #38 — Discussion

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Polygenic Risk Score Prediction of Alcohol Dependence Symptoms Across Population-Based and Clinically Ascertained Samples.
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frequent consumption is still a deviant behavior (Substance Abuse and Mental Health Services Administration, 2014). Age difference between samples is also an important limitation, although we note that previous studies have found that the same genetic factors influence AUDs in both adolescence and adulthood (Palmer et al., 2013), and the replication in the young adult subset of COGA demonstrated consistency of our results.