pregnancy, we were able to address this potential confound. Our primary research question was whether the maximum number of drinks a woman consumed in any 24-hr period in her lifetime would be associated with the same types of characteristics of her adolescent children as paternal maximum alcohol consumption. In addition, we determined whether maternal alcohol dependence diagnoses or paternal maximum consumption might mediate any such associations. Two different large, population-based samples of 17-year-old adolescents were included, providing the opportunity to replicate observed effects and conferring substantial generality to any findings that might obtain.
