paperKB
coga / coga-kb
Help
Sign in

Chunk #55 — Methods — Genomic structural equation modeling

Source
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond.
Embedded
yes

Text

A single latent factor gSEM was used with the residual variance of the latent factor set to 1 to normalize the loading estimates. The loadings were calculated using diagonally weighted least squares and residual variances were bound to above 0.01 to avoid negative residual variance estimates.