controls, we went on to examine in detail all events greater than 2 Mb (Table 4). In this category, we observed 17 events, comprising 8 deletions, all in cases, and 9 duplications, 6 in cases and 3 in controls (Table 4). Fisher's Exact test indicated that such very large events were significantly more prevalent in cases than controls (p = 0.006). However, when we separated these events into deletions and duplications we found that although deletions remained significantly more frequent in cases (p = 0.003), duplications did not (p = 0.33).
