DNA was isolated from approximately 10 mg dry homogenized tissue from specimens coming from the MSSM and Penn brain banks. The thinly sliced tissue from Pitt was homogenized before DNA isolation. All DNA isolation was preformed using the Qiagen DNeasy Blood and Tissue Kit according to the manufacturer’s protocol. DNA yield was quantified using Thermo Scientific’s NanoDrop. The mean yield was 12.6 ug (+/− 4.6), the mean ratio of 260/280 was 2.0 (+/− 0.1), and the mean ratio of 260/230 was 1.8 (+/− 0.6).
