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Chunk #38 — TOP-DOWN PROCESSES - PAC IN VOLUNTARY MOVEMENT

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Alcohol use disorder is associated with increases in frontocentral phase-amplitude coupling strength during resting state.
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It is interesting that AUD, OCD, and PD all represent disorders characterized by some form of dysregulated volition, with loss of voluntary control in OCD compulsive behaviors, patterns of alcohol craving and relapse, and disruptions to smooth initiation of voluntary movement in PD. Perhaps the excessive alpha-gamma and beta-gamma PAC these conditions share reflect dysfunction in overlapping brain networks underlying volitional behavior.