residual genetic variation (i.e. after accounting for variation in SR and CON) in AUD (a33), and any residual genetic variation in MDD (a34) due to AUD. Finally, factor A4 accounts for any genetic variation in the risk for MDD, unexplained by SR, CON, and AUD. This same approach was applied to decompose the unique environmental variation using factors E1, E2, E3, and E4.
