Genotyping for 2,105 subjects in these 118 families was performed at the Genome Technology Access Center at Washington University School of Medicine in St. Louis using the Illumina Human OmniExpress array 12.VI (Illumina, San Diego, CA, USA). In addition, genotypes previously generated on the Illumina Human 1M-Duo BeadChip (Illumina, San Diego, CA, USA) by the Center for Inherited Disease Research were included for 224 subjects from these families (Edenberg et al., 2010). Further details describing data cleaning can be found in Wetherill et al. (Wetherill et al., 2014). The final analytic sample included 2,322 genotyped individuals. This yielded an average of 19.6 genotyped members per family.
