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Chunk #12 — Methods — Overview and baseline data

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A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism.
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oz of nonfortified wine, or a single “shot” of whisky, gin or similar beverages) required for up to 4 effects of alcohol, including first feeling any effect, slurring speech, feeling unsteady when walking, and unwanted falling asleep. The average drinks needed for those effects the approximate first five times of drinking produced the SRE5 score, and the average drinks across the first five times, the period of heaviest drinking, and the recent three months were used to produce the SRE Total (SRET) score (Ray et al., 2011; Schuckit, 2018; Schuckit et al., 2007). The SRE alphas are .90, and up to five-year retest reliabilities are 0.66 (Ray et al., 2011; Schuckit et al., 1997). The SRE5 was developed as a potential measure of a person’s sensitivity and/or intrasession tolerance to alcohol very early in their drinking careers and before intersession tolerance was likely to have developed. The SRET was structured to include reactions to alcohol during periods of heavier drinking that might point toward the development of intersession tolerance. For the SRE, higher average drinks required for effects indicate lower LR values per drink.