Chunk #70 — Methods — Gene term enrichment analysis — Differential expression analysis: gene term enrichment and hypergeometric analysis

Source

Analysis of gene expression in the postmortem brain of neurotypical Black Americans reveals contributions of genetic ancestry.

Embedded

yes

Text

For hypergeometric analysis, we used enrichGO and enrichDGN from the clusterProfiler and DOSE packages, respectively. Like the GSEA analysis, we defined the gene set ‘universe’ as all unique genes tested for differential expression.