Chunk #44 — Methods — Genotyping, imputation, and quality control — RS

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Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.

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After exclusions for call rate<98%, HWE P<10−6, and MAF<1%, 512,349 autosomal SNPs in RS-I and 466,389 autosomal SNPs in RS-II were used for imputation in MACH (version 1.00.15 for RS-I and 1.00.16 for RS-II)65 with reference to the 2,543,887 SNPs of the HapMap CEU (release 22, build 36)70.