We reported widespread medication effects both in adults and children with OCD. However, the current study did not allow a reliable investigation of medication effects because of its cross-sectional design and lack of detailed information on history, duration, type, and dosage of psychotropic treatment. We therefore must interpret our results with caution and cannot make any premature conclusions about the effect of anti-OCD medication. Further efforts, e.g. intervention studies with comparisons before and after medication, are required to draw valid conclusions on the impact of medication use on cortical structure.
