Granger causality has been successfully used to identify coupling (connectivity) and information exchange across brain regions in a variety of clinical conditions, such as developmental dyslexia (Ligges et al. 2010), epilepsy (Adhikari et al. 2013; Chavez et al. 2003), and Alzheimer’s disease (Dauwels et al. 2009, 2010). Studies are being conducted using Granger causality to understand the directionality of the neural pathways across brain regions involved in neural processing in alcoholics and their HR offspring.
