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Chunk #26 — RESULTS — Results in Male–Male Pairs

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The relationship between genetic influences on alcohol dependence and on patterns of alcohol consumption.
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We will again focus here solely on results for the genetic factors. The heritability for AD in this model is estimated at 47%. Of this total genetic effect, 84.5% was shared with our measures of AC. Unlike in females, there was evidence for genetic variance unique to AD (15.5%). Looking at the magnitude of the path from the A1 genetic factor to the 4 forms of AC, maximum quantity best indexes the genetic risk to AD in males, followed by drunk frequency. Looking at the proportion of genetic risk for these forms of AC shared with AD (Table 3), nearly 90% of the genetic risk for drunk frequency and regular quantity was shared with AD, compared to 87% for maximum quantity and 78% for drink frequency.