We utilized 1000 Genomes data for these analyses. Data was obtained from the 1000 genomes website (http://www.1000genomes.org/data), a third party source for population whole genome sequence data. The populations were grouped into EUR (GBR, TSI, CEU, FIN), ASN (CHS, CHB, JPT), and AFR (YRI, LWK, ASW). All methods were calculated for the same regions: the CHRNA5-A3-B4 region on chromosome 15q25, the CHRNB3-A6 region on chromosome 8p11, the LCT region as a positive control on chromosome 2q21, and ten intergenic negative control regions where applicable.
