The second cohort of HD was compared to the first cohort on background characteristics, drinking behavior, and BrAC by t-tests, repeated measures ANOVAs, and χ2 tests as appropriate. In order to compare alcohol response between the cohorts, three sets of analyses were made to test whether our original published results were replicated. First, as prior analyses of the original cohort focused on HD vs. LD comparisons, the first cohort data was reanalyzed independently including HD only on all measures using a repeated measures ANOVA with dose (two levels) and time (three to five levels, depending on the dependent measure being examined) entered as within subject factors. Results for the reanalysis are presented in Table 2.
