Standard anthropometric data and biological samples (blood plasma, blood serum, white blood cells and erythrocytes) were collected from 385,747 of the 519,978 EPIC study participants and 346,055 of 455,680 individuals participating in 8 of the 10 EPIC cohorts included in InterAct. Individuals without stored blood (n=109,625) or without information on reported diabetes status (n=5,821) were excluded, leaving a total of 340,234 participants with 3.99 million person-years of follow-up eligible for inclusion in InterAct (figure 1).