To determine whether the number of first- and second-degree relatives with alcohol and other mental health problems correlated with sensorimotor network connectivity within the premotor cortex region, partial correlations were computed between intranetwork connectivity within this region in relation to the number of first- and second-degree relatives with AUD, mood disorders, and anxiety disorders, controlling for age bin and sex. Number of first-degree relatives with AUD was not correlated with connectivity [r(90) = −0.03, p = .809], but connectivity was correlated with number of second-degree relatives with AUD [r(90) = −0.24, p = .023]. Number of first degree relatives with mood disorders was also negatively correlated with connectivity [r(90) = −0.22, p = .034]. The other correlations with connectivity were not significant (all p > .05).
