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Chunk #29 — METHODS — Genome-wide Analyses in European Ancestry

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Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.
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As the sample size of summary data derived from African Americans (n range = 9,835–56,648) was not sufficient for LD Score54 analyses, we used ASSET24 to conduct the addiction-rf GWAS, as opposed to GenomicSEM, as described in the subsequent ASSET section below.