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Chunk #26 — Method — Polygenic risk scores

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Psychophysiological endophenotypes to characterize mechanisms of known schizophrenia genetic loci.
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each endophenotype in the context of our twin design, we estimated in OpenMx (Boker et al. 2011) correlations and their 95% confidence intervals (Neale & Miller, 1997) using a standard twin family model (Martin & Eaves, 1977) with a shared environmental component estimated in the twins and no shared environment in the parent generation.