For the genome-wide study of de novo CNV associating with schizophrenia the significance threshold was set at 7.6×10−4 which is approximately 0.05/66, the number of de novo CNVs identified and tested. All P-values are two-sided and there is no overlap between samples in Tables 1 and 2. An exact conditional Cochran-Mantel-Haenszel test (conditional on the strata margins) was used to test for association of schizophrenia and the various CNVs.
