The nucleus accumbens has been recognized as a key neural region involved in reward processes. Because alterations in reward functioning are a major candidate for one of the pathophysiolgical mechanisms in ADHD, NAcc-related connectivity is of central importance to examine in this population. Because the NAcc is part of the reward circuit, the atypical interaction between this region and other regions of the circuit was hypothesized to be implicated in atypical reward processing. In trying to understand the role of the NAcc in the pathophysiology of ADHD, a major question arises: which atypical interactions of the NAcc are associated with reward-related processes in ADHD?
