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Chunk #17 — SAMPLE & METHODS — EEG Recording & Processing

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A genome wide association study of fast beta EEG in families of European ancestry.
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use of a Fourier transform. After windowing effects were minimized by application of a Hamming function (Hamming, 1983), the resulting spectral densities, sampled at 0.5 Hz intervals, were aggregated into bands, divided by the bandwidth, and then averaged across epochs. As the elevation of beta power reported in individuals with alcohol use problems has a largely anterior topography, particularly in the higher frequency fast beta band (20–28 Hz; (Rangaswamy et al., 2002)), the current study examines fast beta EEG (20–28 Hz) at fronto-central pairs: Fz-Cz, F3-C3, and F4-C4. Given the high degree of correlation observed among these phenotypes, GWAS results are presented for F3-C3, for which the most robust effects were observed.