The current study had numerous strengths, including a large sample, sophisticated methodological design, and the measurement of multiple domains of subjective response under both ascending and descending BrAC, but it also suffered from some limitations. Notably, participants were alone and engaged in a number of cognitive tasks over the course of the alcohol challenge session. Participants’ social isolation (see Doty & de Wit, 1995), coupled with fatigue due to completing the cognitive tasks, could help to explain the overall low levels of stimulation (and decline in stimulation throughout the session) observed here.