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Chunk #59 — DISCUSSION

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Cross-frequency phase-amplitude coupling in repetitive movements in patients with Parkinson's disease.
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(24, 29, 37). However, as assessed by the movement rate and EMG slope, the behavioral performance in a self-paced repetitive pressing and releasing task did not differ between groups. This finding demonstrates that the motor impairment of patients with PD manifests differently across different voluntary repetitive movements. Because the tasks were associated with different probabilities of revealing Parkinsonian motor impairment, we were able to address the question of whether PAC enhancement was a necessary and sufficient condition for Parkinsonian bradykinesia.