food as the effect of OxoSQ waned, which is reflected by lack of a significant effect on BPs for either cocaine or food. OxoSQ did not significantly compromise motor ability of the animals (Fig 5), and the non-significant locomotor stimulant effect seen was shorter lived than the effects on either food or cocaine responding. The effect of OxoSQ could not be attributed to systemic cholinomimetic effects, because OxoSQ was effective in reducing lever pressing when microinjected in the LDTg but not CIC. Further, there was no significant effect of OxoSQ on locomotor activity, when OxoSQ was microinjected in the CIC (Fig 5B).
