to be expressed at less than 1% of the levels of expression of these major isoforms. CNEX1-10 and 3-12 isoforms are expressed in brain only, where they are likely to participate in regulation of brain-specific calcineurin isoform activity. However, isoforms that are expressed at low levels in whole tissue samples might be selectively expressed in small cell subpopulations where they might play more substantial roles.