We investigated the cell-type–specific expression of the Coloc prioritized genes, using the immunopanning data from humans and mice, and coexpression analysis of the GTEx and Braineac data.15,16,24 From the immunopanning data, cell-type–specific enrichment values were obtained or calculated for each gene and for each cell type analyzed. Enrichment was calculated as expression prevalence by dividing the mean expression of the gene in one cell type by the mean expression across all other cell types. Each gene of interest was then assigned to a primary cell type of interest based on the highest cell-type–specific enrichment value observed.
