of the phenotype or using the largest sample size. We also calculated the genetic correlations of both AUDIT-C and AUD with five traits for which GWAS were recently published or posted, including anorexia nervosa59, alcohol dependence13, attention deficit hyperactivity disorder60, autism spectrum disorder61, and major depressive disorder (summary data without the 23andMe sample)62, bringing the total number of tested traits to 714. A Bonferroni correction was applied separately for AUDIT-C and AUD, and traits with a corrected p value <0.05 were considered significantly correlated. Because the results were similar whether the intercept was constrained or not, we present here the original results without constraint.
