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Chunk #34 — Results — Tobacco Use (TOB) Results

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Principal Component Analysis Reduces Collider Bias in Polygenic Score Effect Size Estimation.
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8 phenotypic PCs were retained in the parallel analysis. Eigenvalues and a Scree plot of the retained components are available in Supplemental Table IV and Supplemental Figure 1, respectively. Change R2 values for the PRS from each model are presented in Table II. Standardized coefficient estimates for PRS and TOB from each model are presented in Table III. Figure 4 displays change in the standardized coefficient estimates for PRS.