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Chunk #0 — Introduction

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Theta event-related synchronization is a biomarker for a morbid effect of alcoholism on the brain that may partially resolve with extended abstinence.
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Fein and colleagues (Andrew and Fein 2010b; Gilmore and Fein 2012) have recently reported increased event-related synchronization (ERS) of induced theta activity in two different samples of long-term abstinent alcoholics (LTAA), compared to age- and gender-comparable controls in a three-condition visual oddball task. Event-related oscillatory activity, extracted with time-frequency (TF) methods, represents frequency-specific event-related changes in the ongoing EEG, and is distinguished by whether they are phase locked to the stimulus (Kalcher and Pfurtscheller 1995; Pfurtscheller and Lopes da Silva 1999). TF activity that is phase locked to the stimulus is referred to as evoked oscillations, while non-stimulus-phase-locked activity is termed induced oscillations (Klimesch et al. 1998). Theta ERS is an increase in induced theta (3–7 Hz) power relative to prestimulus values (Kalcher and Pfurtscheller 1995; Pfurtscheller and Lopes da Silva 1999).