Table 2 presents genotype frequencies by race and family relationship, within group (i.e. control vs. patient) (top panel), case-control analyses (middle panel) and power analyses for those case-control tests (bottom panel). A-allele frequencies ranged from 0.47 to 0.79 within group (patient vs. control, race/ethnicity and family relationship) and are generally lower than that reported by Dick et al., 2006 and others (Drgon et al., 2006); however, the same general pattern (i.e. higher A-allele frequencies seen among African Americans) is seen here. Genotype frequencies for Caucasian (p=0.02) and Hispanic patient probands (p=0.001) and Other patient mothers (p=0.03) deviated from HWE but not for other subgroups (parents and probands).
