The effects of clonidine on water intake during the daily 2-h free-choice between alcohol and water in this 5-day treatment trial are presented in Fig. 4. As in the previous 2-day treatment trial, no commonly used data transformations were effective in achieving homogeneity of variance and normal distribution of the water data, so eight separate non-parametric 1-way ANOVA analyses were conducted, i.e., one each for the Pre-Drug Day, Drug Days 1–5, and Post-Drug Days 3 and 4. Kruskal-Wallis 1-way ANOVA on ranks indicated that water intake was not significantly different among the treatment groups on any day.
