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Chunk #55 — Methods — Gene expression data

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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
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samples enriched for oligodendrocytes, dopaminergic neurons, serotonergic neurons and cortical parvalbuminergic interneurons) that identified 24 broad categories and 149 refined cell types 12; 3) a study that sampled 19,550 nuclei from frozen adult human post-mortem hippocampus and prefrontal cortex and identified 16 cell types 42; 4) a study that generated 36,166 single-nuclei expression measurements (after quality control) from the human visual cortex, frontal cortex and cerebellum 45. We also obtained bulk tissues RNA-seq gene expression data from 53 tissues from the GTEx consortium 8 (v8, median across samples).