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Chunk #42 — 4. Discussion — 4.4 Study Strengths and Limitations

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Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals.
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The study had several methodological strengths including the large, demographically diverse community sample of cocaine dependent adults and closely age-matched siblings. Also, psychiatric and substance dependence disorders were diagnosed using a standardized structured interview (Pierucci-Lagha et al., 2005; 2007). Further, a range of indices of cocaine dependence severity was utilized rather than a single measure of symptom or impairment severity.