also used the first two eigenvectors within the East Asian population (Figure S2) as covariates. The Quantile-Quantile plot of the -values exhibited an inflation factor (; [10]) of 1.01 for the genome-wide SNPs (Figure S3a), which suggests that there was no additional population stratification in our population. In addition, the Quantile-Quantile plot for the genome-wide CNPs also exhibited an inflation factor of 1.05 (Figure S3b), which suggests that there is minimal genotyping error [11] in the CNP data.