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Chunk #45 — DISCUSSION — ERO and PLI analyses in B6 and D2 mice

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Event-related oscillations as risk markers in genetic mouse models of high alcohol preference.
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B6 mice also exhibited reduced delta ERO energy in the 50 to 350 ms time window in the parietal cortex. Since decreased N1b and P3 amplitudes were previously reported in B6 mice (Ehlers and Somes, 2002), lower energy in the delta frequency band may mediate reduced N1b and P3 amplitudes in B6 mice. The present results also demonstrated reduced delta and theta PLI in B6 mice, compared to D2 mice. These findings suggest that decreased N1b and P3 amplitudes are associated with reduced delta and theta PLI. Interestingly, our results also demonstrated higher energy in the evoked frontal theta band in the 350–800 ms time window of B6 mice, compared to D2 mice. Further study is needed to characterize the functional significance of this increase in the energy of the evoked frontal theta band.