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Chunk #27 — RESULTS — Genetically informative research approaches and their limitations — Comorbidity with other psychiatric disorders

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Genetically informative research on adolescent substance use: methods, findings, and challenges.
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In contrast, multiple studies of adolescents suggest that associations between alcohol use and externalizing problems during adolescence are largely attributable to shared environmental influences.66,67 While parental alcohol consumption and dependence have long been recognized as predicting both substance use and externalizing disorders in offspring, twin studies imply that parental alcohol use may link offspring alcohol involvement to other psychopathology via familial environmental mechanisms.