Chunk #12 — Method — GWA analysis

Source

Genome-wide association scan for five major dimensions of personality.

Embedded

yes

Text

To evaluate association on the X chromosome, we modeled a polygenic variance component shared according to an X-linked kinship coefficient in addition to the usual autosomal polygenic variance component (3, 47). Further, we assumed that average phenotypic values for hemizygous males would be the same as for homozygous females (3, 47).