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Chunk #16 — Results — Enrichment of brain cisSNPs among human disease-associated SNPs

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Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
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We also performed comparisons of the eGWAS results from the ADs and non–ADs separately to determine whether there were any results unique to these diagnostic groups (Text S1, Supplementary Tables 12, 13, 14, 15 in Dataset S1). Although 13–25% of the disease/trait associations were with cisSNPs that were unique to ADs or non–ADs, all but a few of these could also be identified in the combined analysis of all subjects. There were only 2–7 human diseases/traits with cisSNP associations that were detectable just in ADs or non–ADs, but not the combined group.